Principal interactions of structural proteins at cadherin-based adherens junction. Actin filaments are linked to ?-actinin and to membrane through vinculin. The head domain of vinculin associates to E-cadherin via ?-, ? - and ? -catenins. The tail domain of vinculin binds to membrane lipids and to actin filaments.

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Principal interactions of structural proteins at cadherin-based adherens junction. Actin filaments are linked to ?-actinin and to membrane through vinculin. The head domain of vinculin associates to E-cadherin via ?-, ? - and ? -catenins. The tail domain of vinculin binds to membrane lipids and to actin filaments.



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